45 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27654218	56	Synthesis and biological evaluation of a series of N-alkylated imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.	Ludwig-Maximilians-Universit£T M£Nchen
27039250	58	Synthesis of 4-substituted nipecotic acid derivatives and their evaluation as potential GABA uptake inhibitors.	Ludwig-Maximilians-Universit£T M£Nchen
26706177	136	Straightforward and effective synthesis of¿-aminobutyric acid transporter subtype 2-selective acyl-substituted azaspiro[4.5]decanes.	Universit£
25147609	18	Conformationally Restricted GABA with Bicyclo[3.1.0]hexane Backbone as the First Highly Selective BGT-1 Inhibitor.	Hokkaido University
25679268	9	A binding mode hypothesis of tiagabine confirms liothyronine effect on¿-aminobutyric acid transporter 1 (GAT1).	University of Vienna
25882526	496	Structure activity relationship of selective GABA uptake inhibitors.	University of Copenhagen
25698617	61	Design, synthesis and SAR studies of GABA uptake inhibitors derived from 2-substituted pyrrolidine-2-yl-acetic acids.	Ludwig-Maximilians-Universit£T M£Nchen
25025595	30	First photoswitchable neurotransmitter transporter inhibitor: light-induced control of¿-aminobutyric acid transporter 1 (GAT1) activity in mouse brain.	Ludwig-Maximilians-Universit£T M£Nchen
24973660	150	Synthesis, biological evaluation and structure-activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides.	Jagiellonian University Medical College
24112084	6	The lignan (-)-hinokinin displays modulatory effects on human monoamine and GABA transporter activities.	Drexel University College of Medicine
23886812	16	Cyclopropane-based conformational restriction of GABA by a stereochemical diversity-oriented strategy: identification of an efficient lead for potent inhibitors of GABA transports.	Hokkaido University
23770450	3	Synthesis of N-substituted acyclicß-amino acids and their investigation as GABA uptake inhibitors.	Zentrum F£R Pharmaforschung
23398473	85	Selective mGAT2 (BGT-1) GABA uptake inhibitors: design, synthesis, and pharmacological characterization.	University of Copenhagen
23336362	10	Focused pseudostatic hydrazone libraries screened by mass spectrometry binding assay: optimizing affinities toward¿-aminobutyric acid transporter 1.	Ludwig Maximilians University At Munich
21940173	32	Aminomethyltetrazoles as potential inhibitors of the¿-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.	Ludwig-Maximilians-University Munich
17517506	14	Synthesis and biological evaluation of (R)-N-(diarylmethylthio/sulfinyl)ethyl/propyl-piperidine-3-carboxylic acid hydrochlorides as novel GABA uptake inhibitors.	Zhengzhou University
16821765	29	Development of peptidic dopamine transporter inhibitors via aromatic modification-mediated conformational restriction.	Chinese Academy of Sciences
16246548	22	Design, synthesis, and biological evaluation of the N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I).	Fudan University
16250647	71	2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization.	Universit£
15509161	90	Novel secoergoline derivatives inhibit both GABA and glutamate uptake in rat brain homogenates: synthesis, in vitro pharmacology, and modeling.	Budapest University of Technology and Economics
10543872	31	Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates.	Novo Nordisk
10479278	70	Synthesis of novel GABA uptake inhibitors. 3. Diaryloxime and diarylvinyl ether derivatives of nipecotic acid and guvacine as anticonvulsant agents.	Novo Nordisk
21353350	61	Development of imidazole alkanoic acids as mGAT3 selective GABA uptake inhibitors.	Ludwig-Maximilians-University Munich
21134748	59	Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors.	Glaxosmithkline
20219271	10	Azetidine derivatives as novel gamma-aminobutyric acid uptake inhibitors: synthesis, biological evaluation, and structure-activity relationship.	Zentrum F£R Pharmaforschung
19703775	24	Synthesis and biological evaluation of 4-fluoroproline and 4-fluoropyrrolidine-2-acetic acid derivatives as new GABA uptake inhibitors.	Institute of Microbiology
	20	On the bioactive conformation of the gaba uptake inhibitor SK&F 89976-A	TBA
30718063	118	Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a cis-alkene spacer as GABA uptake inhibitors.	Ludwig-Maximilians-Universit£T M£Nchen
30777661	42	Screening oxime libraries by means of mass spectrometry (MS) binding assays: Identification of new highly potent inhibitors to optimized inhibitors ?-aminobutyric acid transporter 1.	Ludwig-Maximilians-University M£Nchen
31117514	167	Five-Membered N-Heterocyclic Scaffolds as Novel Amino Bioisosteres at ?-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters.	University of Copenhagen
30503411	15	Generation and screening of pseudostatic hydrazone libraries derived from 5-substituted nipecotic acid derivatives at the GABA transporter mGAT4.	Ludwig-Maximilians-Universit£T M£Nchen
30376325	50	Novel Allosteric Ligands of ?-Aminobutyric Acid Transporter 1 (GAT1) by MS Based Screening of Pseudostatic Hydrazone Libraries.	Ludwig-Maximilians-Universit£T M£Nchen
31097402	13	Application of the concept of oxime library screening by mass spectrometry (MS) binding assays to pyrrolidine-3-carboxylic acid derivatives as potential inhibitors of ?-aminobutyric acid transporter 1 (GAT1).	Ludwig Maximilians-Universit£T M£Nchen
31050421	48	Overview of Recent Strategic Advances in Medicinal Chemistry.	Shandong University
8057281	100	Design, synthesis and evaluation of substituted triarylnipecotic acid derivatives as GABA uptake inhibitors: identification of a ligand with moderate affinity and selectivity for the cloned human GABA transporter GAT-3.	Synaptic Pharmaceutical
23859778	107	2-Substituted 4-hydroxybutanamides as potential inhibitors of ?-aminobutyric acid transporters mGAT1-mGAT4: synthesis and biological evaluation.	Jagiellonian University Medical College
23598250	49	Synthesis and evaluation of N-substituted nipecotic acid derivatives with an unsymmetrical bis-aromatic residue attached to a vinyl ether spacer as potential GABA uptake inhibitors.	Ludwig-Maximilians-University Munich
30442505	61	Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a trans-alkene spacer as potent GABA uptake inhibitors.	Ludwig-Maximilians-Universit£T M£Nchen
29924931	58	Development of New Photoswitchable Azobenzene Based ?-Aminobutyric Acid (GABA) Uptake Inhibitors with Distinctly Enhanced Potency upon Photoactivation.	Ludwig-Maximilians-University Munich
29886082	74	Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors.	Ludwig-Maximilians-Universit£T M£Nchen
28991462	360	Structure-Activity Relationship, Pharmacological Characterization, and Molecular Modeling of Noncompetitive Inhibitors of the Betaine/?-Aminobutyric Acid Transporter 1 (BGT1).	University of Copenhagen